Corey Lactone Diol
High-Purity Synthetic Intermediate for Advanced Pharmaceutical & Chemical Applications
Product Overview
CAS Number: 76704-05-7
Standard: In-House Standard
Corey Lactone Diol is a highly valuable synthetic intermediate widely used in organic chemistry, pharmaceutical development, and fine chemical production. Named after renowned chemist Elias James Corey, it is recognized for its excellent stability, high purity, and reliable stereochemical properties.
Its versatile structure - featuring a lactone ring and two hydroxyl groups - makes it an essential building block for synthesizing complex molecules including pharmaceuticals, prostaglandins, natural products, and agrochemicals.
Key Features & Benefits
- High Purity: ≥98% purity suitable for sensitive synthetic reactions.
- Excellent Stability: Stable under recommended storage conditions.
- Stereochemical Control: Supports production of enantiopure compounds.
- Versatile Reactivity: Ideal for constructing complex molecular frameworks.
Specifications
Chemical Formula: C₈H₁₂O₄
Molecular Weight: 172.18 g/mol
Appearance: White to almost white powder or crystalline solid
Solubility: Soluble in common organic solvents such as methanol and dichloromethane
Optical Activity: Available in optically active forms through optical resolution
Applications
Pharmaceutical Synthesis: Essential intermediate in the production of prostacyclin analogues such as Iloprost, used for pulmonary arterial hypertension and circulatory disorders.
Natural Product Synthesis: Widely used in the synthesis of prostaglandins, hormone analogues, and bioactive organic compounds.
Agrochemical Production: Serves as a key intermediate in advanced pesticide and agricultural chemical manufacturing.
Chiral & Stereoselective Chemistry: Enables production of high-purity diastereomers and enantiomers through enzymatic or chemical resolution methods.
Why Corey Lactone Diol Is Important
- Enables precise stereochemical synthesis for pharmaceutical development.
- Supports efficient and cost-effective synthetic pathways.
- Serves as a core structural building block in multiple industries.
- Delivers reliability, purity, and performance in complex reactions.
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