API Carbetocin (CAS 37025-55-1)
Long-Acting Oxytocin Analog for Postpartum Hemorrhage Prevention & Obstetric Care
Product Overview
Carbetocin is a long-acting synthetic analog of oxytocin widely used to prevent postpartum hemorrhage (PPH), one of the leading causes of maternal mortality worldwide. Its improved stability and prolonged action make it a preferred choice in both routine and high-risk obstetric care.
CAS Number: 37025-55-1
Standard: In-House
Applications
Carbetocin is an important medicine in modern obstetrics and gynecology, particularly for its significant uterotonic effects, which assist in reducing excessive bleeding after childbirth.
1. Prevention of Postpartum Hemorrhage (PPH)
Carbetocin is routinely injected during the third stage of labor - intravenously or intramuscularly - to:
▸ Stimulate powerful and sustained uterine contractions
▸ Support full placental delivery
▸ Maintain a strong uterine tone following birth
▸ Reduce the risk of serious maternal hemorrhage
Carbetocin is particularly useful in low-resource environments where frequent dosing or continuous monitoring are challenging.
2. Use During Cesarean Sections
Carbetocin greatly minimizes the requirement for additional uterotonic medications during C-sections. Its persistent action improves:
▸ Intraoperative bleeding control
▸ Uterine stiffness
Overall surgical results
This makes it a popular choice among obstetric teams looking to improve maternal safety.
3. Gynecological Surgeries
Carbetocin can also be administered prophylactically in uterine procedures, such as hysterectomy or myomectomy, to:
▸ Reduce post-operative bleeding
▸ Improve uterine contractility
▸ Improve recovery outcomes
4. Potential Role in Assisted Reproductive Technologies (ART)
Emerging research offers advantages in treatments such as IVF, where maintaining adequate uterine tone following embryo transfer may help:
▸ Reduce procedural bleeding
▸ Maintain a more stable uterine environment
Additional clinical trials are being conducted to investigate Carbetocin's potential benefits in reproductive medicine.
Summary
Carbetocin offers long-lasting efficacy, enhanced stability, and broad clinical versatility across labor, delivery, and gynecologic procedures. Its proven effectiveness in preventing postpartum hemorrhage makes it a cornerstone medication in global maternal health efforts and a trusted therapeutic option for healthcare professionals.
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