Deslorelin Acetate (CAS 82318-06-7)
A Long-Acting GnRH Agonist for Veterinary Reproductive Control
Deslorelin Acetate is a synthetic gonadotropin-releasing hormone (GnRH) agonist widely used in veterinary medicine to manage and treat reproductive disorders in animals. Through controlled modulation of reproductive hormone release, it provides effective, long-term regulation of fertility and reproductive behavior in both male and female animals.
▸ CAS Number: 82318-06-7
▸ Quality Standard: In-House Standard
▸ Category: Veterinary Hormonal API
Deslorelin Acetate is valued for its prolonged duration of action, predictable performance, and broad applicability across companion and production animals.
Product Overview
Deslorelin Acetate works by initially stimulating and then suppressing the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. This suppression leads to reduced production of sex hormones such as estrogen and testosterone, enabling effective control of reproductive cycles and hormone-dependent conditions.
Key Physicochemical Properties
▸ Molecular Formula: C₆₄H₈₃N₁₇O₁₂
▸ Molar Mass: 1282.48 g/mol
▸ Density: 1.48 ± 0.1 g/cm³ (predicted)
▸ Melting Point: >189 °C
▸ Boiling Point: 1783.4 °C at 760 mmHg
▸ Specific Rotation (α): D²⁴ −61° (c = 0.37 in 0.1 M acetic acid)
▸ Flash Point: 1032.4 °C
▸ Solubility: Slightly soluble in acetic acid, DMSO, and methanol
▸ Vapor Pressure: 0 mmHg at 25 °C
▸ Appearance: Powder
▸ Color: White to off-white
▸ pKa: 9.82 ± 0.15 (predicted)
▸ Storage Conditions: Store at 2–8 °C
Mechanism of Action
As a GnRH agonist, Deslorelin Acetate initially stimulates the pituitary gland, followed by down-regulation of GnRH receptors with continued exposure. This results in:
▸ Suppressed LH and FSH secretion
▸ Reduced sex hormone production
▸ Long-term control of reproductive activity
This mechanism makes deslorelin particularly effective for chronic reproductive management rather than short-term ovulation induction.
Veterinary Applications
Deslorelin Acetate is extensively used in veterinary medicine for managing hormone-related reproductive conditions.
Applications in Female Animals
▸ Synchronization of the estrous cycle
▸ Treatment of persistent estrus
▸ Management of ovarian cysts
▸ Support for controlled breeding programs
Applications in Male Animals
▸ Treatment of cryptorchidism (undescended testicles)
▸ Management of benign prostatic hyperplasia (BPH)
▸ Control of testosterone-related behavioral issues
▸ Supportive therapy for testicular tumors
Administration & Duration of Effect
Deslorelin Acetate is typically administered by injection or implant , depending on the formulation. Its effects may last from several weeks to several months , offering sustained hormone control with minimal handling.
When used according to veterinary guidance, it is generally well tolerated and may be combined with other treatments or management strategies for optimal results.
Key Advantages
Long-Lasting Hormonal Control
▸ Extended suppression of reproductive hormones
▸ Reduced need for frequent dosing
Broad Veterinary Utility
▸ Suitable for both male and female animals
▸ Effective in companion and production animals
Proven Safety Profile
▸ Well tolerated when used as directed
▸ Predictable and consistent outcomes
Our Strengths
▸ Qualified Manufacturer: Experienced in veterinary pharmaceutical APIs
▸ Reliable Quality Control: Strict in-house testing and process monitoring
▸ Competitive Pricing: Factory-direct supply ensures cost efficiency
Frequently Asked Questions (FAQs)
Q1: When was your company established?
A: Henan Medscience Pharmaceuticals was established in 2019 .
Q2: Do you accept small-quantity orders?
A: Yes. Small orders are welcome and may serve as a starting point for long-term cooperation.
Q3: Can you provide samples for evaluation?
A: Yes, samples are available for quality analysis upon request.
Q4: What payment methods do you accept?
A: We accept T/T and L/C .
Q5: Do you offer discounts for bulk orders?
A: Yes. Discounts are available for large-volume purchases.
Conclusion
Deslorelin Acetate (CAS 82318-06-7) is a powerful and reliable GnRH agonist that supports long-term reproductive control in veterinary medicine. Its effectiveness in managing hormone-dependent reproductive disorders, combined with extended duration and safety, makes it an essential API for modern veterinary pharmaceutical formulations.
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