API Leuprolide Acetate
A Potent GnRH Superagonist for Advanced Endocrine Therapy
Product Overview
Leuprolide Acetate is a synthetic nonapeptide and a potent superagonist of the Gonadotropin-Releasing Hormone Receptor (GnRHR) . It is a cornerstone in the treatment of hormone-dependent conditions, providing precise control over the production of sex hormones in both human and veterinary medicine.
Product Name: Leuprolide Acetate API
CAS Number: 53714-56-0
Quality Standard: In-House / IP / EP / BP
Category: Endocrine & Reproductive Therapy (API)
As a leading supplier, Henan Medscience Pharmaceuticals provides high-purity Leuprolide Acetate that meets the most stringent global healthcare standards.
Mechanism of Action
Leuprolide acetate operates through a sophisticated biphasic physiological response:
▸ Initial Stimulation: Triggers a temporary surge in Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH).
▸ Downregulation: Continuous administration desensitizes pituitary receptors.
▸ Hormonal Suppression: Effectively reduces testosterone and estrogen to castrate or post-menopausal levels.
This targeted suppression is critical for halting the progression of hormone-sensitive disorders.
Key Applications
1. Oncology & Women's Health
Leuprolide is widely utilized in the management of:
▸ Prostate Cancer: As a form of androgen deprivation therapy.
▸ Endometriosis & Uterine Fibroids: To alleviate pain and reduce lesion size.
2. Pediatric & Reproductive Medicine
Essential for specialized treatments including:
▸ Central Precocious Puberty: Delaying early onset in children.
▸ Infertility Protocols: Assisting in controlled ovarian stimulation.
Technical Specifications
| Property | Specification |
|---|---|
| Molecular Formula | C 59 H 84 N 16 O 12 S 2 |
| Molecular Weight | 1269.5 g/mol |
| Appearance | White to off-white lyophilized powder |
| Solubility | Freely soluble in water |
Quality & Manufacturing
At Henan Medscience Pharmaceuticals Co., Ltd. , quality is our primary mandate. Our Leuprolide Acetate is produced in a GMP-certified environment using advanced synthesis technologies. Every batch is subjected to rigorous testing for:
▸ HPLC Purity & Related Substances
▸ Potency (Bioassay)
▸ Endotoxin Levels & Residual Solvents
Conclusion
Leuprolide Acetate API (CAS 53714-56-0) offers unmatched efficacy in managing hormone-dependent disorders. By choosing Henan Medscience, you partner with a manufacturer committed to technical excellence and global regulatory compliance.
Hot Tags: hormone therapy leuprolide acetate, China hormone therapy leuprolide acetate manufacturers, suppliers, factory, fermentation derived proteins, api integrations with analytics platforms, api integrations for energy companies, api best practices, traceable peptides, peptide purification
