Terlipressin Acetate

CAS Number: 14636-12-5 | Standard: In-House Standard

Terlipressin Acetate is a long-acting synthetic analog of vasopressin widely used in the treatment of bleeding esophageal varices and other critical vascular disorders. As an inactive prodrug, it is converted in the body into lysine vasopressin, providing a prolonged therapeutic effect.

Product Details

Molecular Formula	C52H74N16O15S2
Molar Mass	1227.37
Density	1.46±0.1 g/cm³ (Predicted)
Melting Point	>170°C (dec.)
Boiling Point	1824.0±65.0°C (Predicted)
Flash Point	1056.9°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Pressure	0 mmHg at 25°C
Appearance	Solid
Color	White
pKa	9.90±0.15 (Predicted)
Storage Condition	Keep in dark place, inert atmosphere, store in freezer under -20°C

Applications

Terlipressin Acetate is a key medication in emergency and acute care medicine because of its potent vasoconstrictor properties.

1. Management of Esophageal Variceal Bleeding

First-line treatment for acute variceal hemorrhage with proven survival benefits. Its long-acting profile enables sustained hemorrhage control.

2. Support for Hepatorenal Syndrome (HRS)

Improves liver and kidney function in patients awaiting liver transplantation, helping prolong survival time.

3. Shock and Resuscitation

▸ Refractory shock

▸ Cardio-pulmonary resuscitation (CPR)

▸ Severe intraoperative hypotension

▸ Pediatric cardiac arrest

Its strong vasopressor effect makes it essential in emergency management.

Our Strengths

Extensive Production Experience

Over ten years of pharmaceutical manufacturing experience serving global customers.

Complete GMP-Compliant Manufacturing System

2,523 m² facility including a 365 m² Class D clean area, fully operated according to GMP standards.

Strict Quality Control

Comprehensive quality management from raw material sourcing to final release, ensuring purity and stability.

Excellent Customer Service

Regulatory documentation support, technical assistance, and customized solutions with timely response.

FAQ

Q: Have you exported products in recent years?

Yes. Our products are exported to India, South America, the Middle East, and European Union countries with a strong reputation for quality and reliability.