Atosiban Acetate
CAS Number: 914453-95-5 | Standard: In-House Standard
Introduction
Atosiban Acetate is a competitive antagonist of the cyclic peptide oxytocin receptor located in the uterus, decidua, and fetal membranes.
It is a synthetic peptide analogue of oxytocin designed for use as a uterine relaxant (tocolytic agent). By competitively inhibiting oxytocin receptors in uterine smooth muscle, it suppresses contractions and reduces the risk of preterm labor.
As an active pharmaceutical ingredient (API), Atosiban Acetate is manufactured under strict GMP conditions to ensure high purity, stability, and consistency for pharmaceutical formulation and clinical use.
Product Details
| Molecular Formula | C45H71N11O14S2 |
| Molar Mass | 1054.25 |
| Melting Point | >165°C (dec.) |
| Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | Store at 4°C |
Applications
Atosiban Acetate is primarily indicated for the management of preterm labor in pregnant women between 24 and 33 weeks of gestation.
▸ Administered intravenously
▸ Initial bolus injection followed by continuous infusion
▸ Alternative higher-dose bolus depending on clinical condition
Clinical studies have demonstrated its efficacy in delaying preterm birth, improving neonatal outcomes, and reducing complications associated with premature delivery.
The drug is generally well tolerated, with mild and transient side effects such as nausea, dizziness, headache, or vomiting occasionally reported.
Due to its targeted mechanism and favorable safety profile, Atosiban Acetate remains a preferred option in obstetric care. Administration should always be performed under medical supervision.
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FAQ
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We are a direct manufacturer with our own production facility, offering competitive pricing and reliable supply.
Q2: How do you guarantee product quality?
▸ Well-developed quality management system
▸ Strict in-process controls
▸ Comprehensive batch testing
▸ Full GMP compliance
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