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Leuprorelin Acetate CAS 74381-53-6
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Leuprorelin Acetate CAS 74381-53-6

Leuprorelin Acetate CAS 74381-53-6

CAS Number: 74381-53-6
Standard: In-House Standard
Leuprorelin acetate is a synthetic hormone analogue used to treat prostate cancer and endometriosis.
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Product Introduction

Leuprorelin Acetate

A Powerful Synthetic GnRH Agonist for Oncology, Endocrinology, and Reproductive Medicine

Product Overview

Leuprorelin Acetate is a powerful synthetic counterpart of gonadotropin-releasing hormone (GnRH) commonly employed in current hormone-regulating treatments. It is primarily used to treat prostate cancer, endometriosis, uterine fibroids, and precocious puberty by providing consistent hormone suppression that slows disease development and improves patient outcomes.

Leuprorelin Acetate is a high-purity pharmaceutical API intended for human medicinal application. As a potent GnRH agonist, it initially increases but then substantially inhibits LH and FSH secretion, resulting in lower testosterone levels in males and lower estrogen levels in women. Because of its tailored hormonal reduction, it is a must-have in oncology, reproductive medicine, and endocrine therapy.

Specifications

Molecular Formula C61H88N16O14
Molar Mass 1269.47
Melting Point 150–155°C
Boiling Point 1720.5°C at 760 mmHg
Flash Point 994.3°C
Solubility DMSO (Slightly), Methanol (Slightly)
Vapor Pressure 0 mmHg at 25°C
Appearance Solid
Color White to Off-White
Storage Condition -20°C

Applications

Leuprorelin Acetate is commonly utilized to create long-acting injectable medicines for a variety of clinical applications:

1. Prostate Cancer Treatment

It significantly lowers testosterone production, limiting tumor growth and serving as a key component of androgen deprivation therapy. Often paired with surgery or radiation to improve treatment success.

2. Endometriosis Management

Leuprorelin Acetate reduces estrogen levels, which helps shrink endometrial tissue, relieve pelvic pain, and improve overall quality of life.

3. Uterine Fibroids

It reduces the size of fibroids and relieves severe bleeding and pain; it is frequently administered prior to surgery to control symptoms.

4. Precocious Publicity

For children with early puberty, Leuprorelin Acetate suppresses premature hormone activity, allowing for normal growth and development.

5. Assisted Reproductive Technology (ART)

Used to manage ovulation timing, synchronize menstrual cycles, and boost IVF success rates.

Our Manufacturing Strengths

Significant Production Expertise

Our team has years of professional pharmaceutical production experience and can give expert help and trusted solutions.

GMP-Compliant Manufacturing System

Our GMP-certified 2,523 m² workshop , which includes a 365 m² Class D clean room , ensures consistent and reliable output.

Tight Quality Control

From raw material selection to environmental monitoring, every step of our process adheres to strict quality standards to assure exceptional product purity and safety.

Outstanding Customer Support

Customer satisfaction is at the heart of our service. We provide technical help, documentation, and solutions that are suited to your specific requirements.

Frequently Asked Questions

Q1: Is your company a manufacturer or a trading firm?
We are a direct manufacturer with our own GMP-compliant production plant, offering competitive pricing and stable supply.

Q2: How do you ensure product quality?
We maintain a comprehensive quality assurance system that includes instrument calibration, personnel training, material qualification, and strict production monitoring.

Conclusion

Leuprorelin Acetate Pharmaceutical Grade is an indispensable GnRH agonist API with a broad spectrum of clinical applications spanning oncology, reproductive medicine, and endocrine therapy. Its proven ability to reliably suppress hormone activity makes it essential in the treatment of prostate cancer, endometriosis, uterine fibroids, precocious puberty, and ART protocols. Manufactured under GMP-compliant conditions with rigorous quality control, it meets the highest standards required by pharmaceutical formulators and healthcare providers worldwide.

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