Cetrorelix Acetate
A Synthetic GnRH Antagonist for Controlled Ovarian Stimulation and Fertility Treatment
Product Overview
Cetrorelix Acetate is a synthetic gonadotropin-releasing hormone (GnRH) antagonist used to treat infertility. It is a synthetic decapeptide - a man-made hormone that acts by blocking the effects of natural GnRH.
CAS Number: 120287-85-6
Quality Standard: In-House / IP Standard
Category: Human Reproductive Active Pharmaceutical Ingredient (API)
Mechanism of Action
By competing with endogenous GnRH for binding to receptors on pituitary cells, Cetrorelix inhibits the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This prevents the LH surge, ultimately controlling the timing of ovulation.
▸ Binds competitively to GnRH receptors on pituitary cells
▸ Inhibits release of LH and FSH
▸ Prevents premature LH surge and early ovulation
▸ Enables precise control over the timing of follicular maturation
Product Details
| Molar Mass | 1431.04 |
| Density | 1.42 ± 0.1 g/cm³ (Predicted) |
| Melting Point | >259°C (dec.) |
| Solubility | DMSO (Slightly, Heated), Methanol (Very Slightly) |
| Appearance | Powder |
| Color | White to Off-White |
| pKa | 9.82 ± 0.15 (Predicted) |
| Storage Condition | Refrigerator |
Applications
1. Assisted Reproductive Technology (ART)
Cetrorelix Acetate is primarily used in assisted reproductive technology to prevent early ovulation during controlled ovarian stimulation. GnRH regulates the release of luteinizing hormone (LH), which triggers ovulation in the menstrual cycle. During hormone treatments, premature ovulation can sometimes occur, leading to the release of eggs that are not yet mature enough for fertilization. Cetrorelix Acetate helps prevent the early release of these immature eggs.
2. Controlled Ovarian Stimulation
In women, Cetrorelix Acetate works by delaying the LH surge, which in turn delays ovulation. This helps control ovarian stimulation, preventing the premature release of immature follicles and aiding in the process of conception. It is commonly used as part of the preparation for injection in fertility treatments.
Our Manufacturing Strengths
Extensive Production Experience
We have 10 years of pharmaceutical production experience. We are a team that can support you with our professionalism.
Accomplished Manufacturing System
We have a workshop that complies with GMP standards and measures 2,523 m² , with a Class D clean area of 365 m² .
Strict Quality Control
To provide the best quality, we make sure to be strict with every step of production, including raw materials control and environment control.
Excellent Customer Support
Our top priority is always customer satisfaction. We can provide full documentation for registration, as well as tailored solutions to meet your needs.
Frequently Asked Questions
Q1: What are the applicable fields of your products?
Our products are widely used in reproduction, endocrinology, and gynecology for both human and veterinary.
Q2: Is your company a manufacturer or trading company?
We have a factory which carries out the whole set of production processes. We sell our high-quality products directly at competitive pricing.
Conclusion
Cetrorelix Acetate Pharmaceutical Grade (CAS 120287-85-6) is an essential API in modern assisted reproductive technology. Its precise GnRH antagonist mechanism enables reliable prevention of premature ovulation, making it a cornerstone ingredient in IVF and controlled ovarian stimulation protocols worldwide. Produced under GMP-compliant conditions with stringent quality control, it meets the exacting standards required by fertility clinics and pharmaceutical manufacturers globally.
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