Urokinase – High-Purity Thrombolytic Enzyme for Clinical Use
A Naturally Occurring Enzyme for Blood Clot Dissolution and Healthy Circulation
▸ CAS Number: 9039-53-6
▸ Standard: In-House / IP / EP / BP Standard
Urokinase is a naturally occurring human enzyme responsible for dissolving blood clots and maintaining healthy blood circulation. As a highly effective thrombolytic agent, it plays a critical role in modern medicine, especially in the treatment of life-threatening clot-related conditions.
Product Overview
Urokinase, also known as urokinase-type plasminogen activator (uPA), is a potent enzyme that converts plasminogen to plasmin - an essential step in breaking down harmful blood clots. Its thrombolytic ability makes it an indispensable medication in emergency and clinical care, particularly for cardiovascular and neurological conditions.
Key Applications of Urokinase
Urokinase is widely used in hospitals and critical care settings due to its rapid and reliable clot-dissolving action. Below are its major clinical applications:
1. Acute Ischemic Stroke Treatment
In ischemic stroke, a blood clot blocks blood flow to the brain, causing rapid tissue damage. Urokinase helps by:
▸ Breaking down the clot
▸ Restoring blood flow
▸ Reducing neurological damage
▸ Improving patient recovery outcomes
It remains a valuable therapeutic option when rapid thrombolysis is required.
2. Deep Vein Thrombosis (DVT)
Urokinase is successfully used to treat deep vein thrombosis, a condition where clots form in deep veins, usually in the legs. It helps:
▸ Dissolve thrombi
▸ Restore circulation
▸ Reduce the risk of complications such as post-thrombotic syndrome
3. Pulmonary Embolism (PE)
In cases of pulmonary embolism - where clots travel to the lungs - urokinase can be life-saving. Clinical benefits include:
▸ Rapid breakdown of emboli
▸ Relief from severe chest pain and breathing difficulty
▸ Prevention of cardiovascular collapse in serious cases
4. Thrombosis Prevention
Patients at high risk of clot formation may receive controlled doses of urokinase to prevent thrombosis. This includes individuals undergoing surgery, prolonged immobilization, or specific cardiovascular treatments.
5. Peritoneal Dialysis Support
In peritoneal dialysis, urokinase is sometimes added to dialysis fluid to prevent:
▸ Fibrin accumulation
▸ Catheter blockage
▸ Dialysis complications
Its fibrin-preventing action makes dialysis smoother and safer for patients.
Why Choose Our Urokinase
1. Completed Manufacturing System
Our manufacturing facility spans 2,523 m², including 365 m² of Class D cleanroom space, built strictly according to GMP standards to ensure top-tier product quality and safety.
2. Strict Quality Control
Every production stage is monitored with rigorous quality protocols, covering:
▸ Raw material inspection
▸ Environmental control
▸ In-process and final product testing
This ensures consistent purity, activity, and compliance with global pharmacopeial requirements.
3. Excellent Customer Service
Customer satisfaction is at the core of our mission. We provide comprehensive support - from technical assistance to order follow-up - to ensure a seamless business experience.
Frequently Asked Questions (FAQs)
Q1: In which fields are your products commonly used?
Our products are widely applied in reproduction, endocrinology, and gynecology, serving both human and veterinary healthcare needs.
Q2: Can we visit your factory for a quality audit?
Yes. We welcome customers for onsite audits. Please contact us to schedule a visit - our team will fully support your inspection and requirements.
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