Maropitant Citrate (CAS 147116-67-4)
Product Details & Chemical Information
| Specification | Details |
|---|---|
| CAS Number | 147116-67-4 |
| Molecular Formula | C₃₂H₄₀N₂O |
| Molar Mass | 468.67 g/mol |
| Density (Predicted) | 1.11 ± 0.1 g/cm³ |
| Boiling Point (Predicted) | 572.6 ± 50.0 °C |
| Vapor Pressure | 0–0 Pa at 20–25 °C |
| pKa (Predicted) | 9.99 ± 0.70 |
| Appearance | Powder |
| Color | White to pale yellow |
| Solubility | Soluble in water and ethanol |
| Storage Condition | 2–8 °C |
What is Maropitant Citrate?
Maropitant Citrate is a potent NK-1 receptor antagonist developed for veterinary use. It blocks substance P from binding to central and peripheral NK-1 receptors, effectively preventing the transmission of emetic signals. It is the active ingredient in Cerenia , widely used for treating nausea and vomiting in dogs and cats.
Veterinary Applications
✔ Prevention & Treatment of Vomiting
Used to manage vomiting caused by:
- Motion sickness
- Chemotherapy
- Gastrointestinal diseases
- Infections and inflammation
- Toxin exposure
- Post-operative nausea
✔ Motion Sickness in Dogs
Provides prophylactic and therapeutic relief from travel-induced vomiting.
✔ GI-Related Nausea & Vomiting
Effective against vomiting caused by gastritis, pancreatitis, and other digestive disorders.
✔ Chemotherapy-Induced Emesis
Central NK-1 antagonistic action helps manage nausea from anti-cancer therapies.
Benefits & Advantages
- ✔ Effective Against Multiple Causes of Vomiting
- ✔ Well-Tolerated by Dogs and Cats
- ✔ Flexible Formulations: Tablets & Injectable Solutions
- ✔ Rapid Action via Central Vomiting Center Targeting
Packaging & Delivery
Shipping options for global clients include:
- Express delivery (FedEx, DHL)
- Air transportation for fast and efficient shipping
- Customized packaging upon request
Sales & Services
Xiamen Origin provides global distribution with high-quality products and responsive support to regions including Europe, North and South America, the Middle East, and Asia.
Frequently Asked Questions (FAQ)
Q: Do you have your own factory?
A: Yes, we operate our own manufacturing facilities.
Q: Can I request customized packaging or transport options?
A: Absolutely. Packaging and shipment methods can be customized according to your requirements.
Conclusion
Maropitant Citrate is a selective NK-1 receptor antagonist essential for managing nausea and vomiting in veterinary medicine. With proven efficacy, favorable safety, and flexible formulation options, it is a core API for modern veterinary anti-emetic therapies.
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