Product Overview

Robenacoxib is a selective COX-2 inhibitor that reduces the production of pro-inflammatory prostaglandins, alleviating pain and inflammation while protecting gastrointestinal and renal function.

Physical & Chemical Properties

• Molecular Formula: C16H13F4NO2
• Molar Mass: 327.27 g/mol
• Appearance: White to off-white solid
• Density: 1.407 ± 0.06 g/cm³ (Predicted)
• Melting Point: 152–155°C
• Solubility: Slightly soluble in DMSO and methanol
• pKa: 4.16 ± 0.10 (Predicted)
• Storage: Keep in airtight container, protected from light

Mechanism of Action

Robenacoxib selectively inhibits COX-2 enzymes, sparing COX-1. This reduces pro-inflammatory prostaglandins, resulting in:

• Alleviation of pain
• Reduction of inflammation
• Maintaining gastrointestinal and renal safety

Its short half-life and rapid elimination allow precise dosing, especially useful for controlling acute pain while minimizing side effects.

Key Applications in Veterinary Medicine

✔ Osteoarthritis Management

Provides long-lasting relief from joint pain and inflammation, improving mobility and quality of life in dogs and cats.

✔Postoperative Pain Control

Reduces pain and inflammation after surgery, supporting faster recovery and enhanced comfort.

✔ Musculoskeletal Disorders

Alleviates discomfort from strains, sprains, and other musculoskeletal conditions, promoting activity and healing.

Advantages of Robenacoxib

• Selective COX-2 inhibition minimizes gastrointestinal and renal risks
• Rapid onset and short half-life allow flexible, safe dosing
• Well-tolerated in most animals with minimal adverse effects
• Veterinary-focused formulation ensures optimal safety and efficacy

Safety Considerations

Robenacoxib should only be administered under veterinary supervision. Rare adverse effects may include:

• Gastrointestinal upset
• Kidney issues
• Altered liver enzyme levels

Routine monitoring is recommended during prolonged administration.

Packaging & Delivery

Robenacoxib can be supplied in customized packaging including glass containers and foil bags. Delivery options include express courier services (FedEx, DHL) or air transport to domestic and international markets.

About the Manufacturer

Henan Medscience produces Robenacoxib under strict quality control standards, exporting to Europe, North America, South America, the Middle East, and Asia with high praise for product quality, technical support, and services.

Conclusion

Robenacoxib (CAS 220991-32-2) is a safe, selective, and effective NSAID for managing pain and inflammation in companion animals. Its targeted COX-2 inhibition, rapid onset, and favorable safety profile make it an excellent choice for veterinarians treating osteoarthritis, postoperative pain, and musculoskeletal disorders in dogs and cats.