Mavacoxib (CAS 170569-88-7)
A Long-Acting COX-2 Selective NSAID for Veterinary Pain and Inflammation Management
Mavacoxib , identified by CAS Number 170569-88-7 , is a highly non-steroidal anti-inflammatory drug (NSAID) widely used in veterinary medicine-primarily for the treatment of osteoarthritis and chronic pain in dogs . As a selective COX-2 inhibitor , Mavacoxib reduces inflammation and pain while minimizing effective adverse gastrointestinal and renal effects commonly associated with non-selective NSAIDs.
Its long duration of action and strong safety profile make it a preferred active pharmaceutical ingredient (API) in modern veterinary formulations.
Product Details & Chemical Information
| Specification | Details |
|---|---|
| CAS Number | 170569-88-7 |
| Molecular Formula | C₁₆H₁₁F₄N₃O₂S |
| Molar Mass | 385.34 g/mol |
| Density (Predicted) | 1.51 ± 0.1 g/cm³ |
| Melting Point | 167–169 °C |
| Boiling Point (Predicted) | 519.8 ± 60 °C |
| Solubility | Soluble in DMSO |
| pKa (Predicted) | 9.67 ± 0.10 |
| Appearance | Solid |
| Color | Off-white to pale beige |
| Storage Condition | 2–8 °C |
These physicochemical properties ensure excellent stability and consistent performance when formulated into veterinary medicines.
What is Mavacoxib?
Mavacoxib is a potent active pharmaceutical ingredient (API) belonging to the NSAID class. Its therapeutic effects come from selectively inhibiting cyclooxygenase-2 (COX-2) -the enzyme mainly responsible for producing inflammatory prostaglandins.
By targeting COX-2 more specifically than COX-1, Mavacoxib delivers strong anti-inflammatory and analgesic effects with a lower risk of gastrointestinal and renal complications .
Thanks to its long half-life, Mavacoxib offers prolonged pain relief, making it particularly suitable for chronic conditions.
Veterinary Applications
✔Osteoarthritis Management in Dogs
Osteoarthritis is a common degenerative joint disease in aging dogs, leading to:
- Joint pain
- Stiffness
- Reduced mobility
- Decreased quality of life
Mavacoxib effectively controls inflammation in affected joints, providing sustained relief and improving mobility.
✔Treatment of Pain and Inflammation from Other Conditions
Beyond osteoarthritis, Mavacoxib is also beneficial for managing:
- Postoperative pain
- Soft tissue injuries
- Musculoskeletal inflammation
- Chronic degenerative conditions
Its long-acting nature reduces the dosing frequency, improving compliance for pet owners.
✔ Advantages Over Traditional NSAIDs
Because Mavacoxib is highly selective for COX-2, it:
- Reduces gastrointestinal irritation
- Lowers renal toxicity risk
- Provides a safer long-term therapy option
- Offers prolonged pain control with fewer doses
These features make it a popular choice among veterinarians for chronic pain management.
Benefits of Mavacoxib API
- High therapeutic potency for inflammation reduction
- Fewer side effects due to COX-2 selectivity
- Ideal for chronic use because of extended duration of action
- Improves overall activity and comfort in dogs with osteoarthritis
- High purity and quality when produced under strict in-house standards
Packaging & Delivery
We offer flexible packaging options to meet global customer needs:
- Customizable packaging (glass bottles, foil bags, small or bulk quantities)
- Fast delivery via express couriers (eg, FedEx)
- Air transportation for international shipments
FAQs
Q: Can the package of your products be customized?
A: Yes. Various packaging sizes and materials can be provided, from small sample packs to full bulk packaging.
Q: How do you deliver your products?
A: Products can be shipped by express services like FedEx or via air freight depending on customer requirements.
Conclusion
Mavacoxib (CAS 170569-88-7) is an essential veterinary API that provides safe, effective, and long-lasting pain and inflammation relief for dogs-especially those suffering from osteoarthritis. With its strong COX-2 selectivity, reduced side-effect profile, and superior pharmacological performance, Mavacoxib represents a trusted solution for improving canine comfort and mobility.
Its stability, high purity, and excellent therapeutic value make it a preferred choice for veterinary pharmaceutical manufacturers worldwide.
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