Trilostane
A Potent 3β-Hydroxysteroid Dehydrogenase Inhibitor for Veterinary and Human Medicine
Product Overview
Trilostane is a potent 3β-hydroxysteroid dehydrogenase inhibitor widely used in veterinary medicine. It is primarily indicated for the treatment of Cushing's syndrome (hyperadrenocorticism) and primary hyperaldosteronism, helping restore hormonal balance by reducing excessive corticosteroid production.
This active pharmaceutical ingredient (API) is also beneficial in treating several species-specific endocrine disorders and certain dermatological conditions in dogs.
Quality Standard: In-House Standard
Category: Veterinary / Human Active Pharmaceutical Ingredient (API)
Trilostane is a reliable and effective hormone production inhibitor that is appropriate for the creation of veterinary formulations.
Product Details
| Molecular Formula | C20H27NO3 |
| Molar Mass | 329.43 |
| Density | 1.1213 (rough estimate) |
| Melting Point | 264°C |
| Boiling Point | 467.02°C (rough estimate) |
| Specific Rotation (α) | D25 +137.4° (c = 1 in pyridine) |
| Flash Point | 254.8°C |
| Solubility | DMSO: ≥17mg/mL |
| Vapor Pressure | 5.39E-12 mmHg at 25°C |
| pKa | 8.57 ± 0.70 (Predicted) |
| Refractive Index | 1.5614 (estimate) |
| Appearance | Powder |
| Color | White to almost white |
| Storage Condition | In an airtight container |
Applications
Trilostane is widely used because of its ability to inhibit steroid production, making it useful in a variety of endocrine disorders.
1. Veterinary Use
▸ Pituitary-dependent hyperadrenocorticism (PDH) in dogs
▸ Adrenal-dependent Hyperadrenocorticism (ADH)
▸ Feline PDH
▸ Equine Hyperadrenocorticism (HAC)
▸ Alopecia X in Pomeranians
▸ Adult onset alopecia in Alaskan Malamutes
It alleviates symptoms such as hair loss, weight gain, excessive thirst, and recurring infections by lowering cortisol and aldosterone levels.
2. Human Use
While largely a veterinary drug, Trilostane has also shown promise in managing:
▸ Primary Hyperaldosteronism
▸ Breast cancer that returns after menopause
Packaging & Delivery
To fulfill the needs of our global clients, we provide a variety of secure and efficient transportation methods.
▸ Express shipping: DHL, FedEx
▸ Air Freight
Product integrity is ensured throughout transit by using safe, moisture-resistant packaging.
Sales and Service Commitment
Xiamen Origin is committed to providing high-quality APIs backed by extensive technical experience and exceptional customer service. Our products are trusted throughout Europe, North America, South America, the Middle East, and Asia. We maintain long-term relationships by providing constant quality, affordable pricing, and dependable delivery.
FAQ
Competitive Price
All Trilostane goods are straight from our plant, ensuring a cost-effective and consistent supply.
Inquiry Format
To obtain an exact quote, please include:
▸ Required quantity
▸ Specifications
Purchase schedule
▸ Delivery terms
Products in Stock
Most of our products, including Trilostane, are available in stock for fast dispatch. Contact us anytime for immediate support.
Conclusion
Trilostane Pharmaceutical Grade is a highly effective and versatile 3β-hydroxysteroid dehydrogenase inhibitor with broad applications across veterinary and human medicine. From treating Cushing's syndrome and hyperaldosteronism to managing dermatological conditions, its targeted hormonal inhibition delivers reliable and consistent clinical results. With in-stock availability, global shipping, and a commitment to quality, Trilostane remains an essential API for pharmaceutical formulation worldwide.
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