Pimobendan (CAS 74150-27-9)
An Advanced Inodilator for Canine Congestive Heart Failure Management
Product Overview
Pimobendan is an advanced veterinary medication widely used in the management of congestive heart failure (CHF) in dogs. It is especially indicated for dogs with dilated cardiomyopathy (DCM) or chronic mitral valve insufficiency (CMVI) - two of the most causes of heart failure in canine common patients. Pimobendan improves cardiac function by increasing myocardial contractility and promoting vasodilation, ultimately enhancing blood flow and reducing cardiac workload.
CAS Number: 74150-27-9
Quality Standard: EP 10.0, In-House Standard
Category: Veterinary Active Pharmaceutical Ingredient (API)
Pimobendan is an effective inodilator (both inotropic and vasodilator), giving dual benefits necessary for better cardiac output and clinical stability in dogs with heart failure.
Product Details
| Molecular Formula | C19H18N4O2 |
| Molar Mass | 334.37 |
| Storage Condition | -20℃ |
| Refractive Index | 1.692 |
| Solubility | DMSO: soluble 5mg/mL, clear (warmed) |
| pKa | 10.55 ± 0.10 (Predicted) |
| Appearance | Powder |
| Color | White or slightly yellowish |
| Storage Condition | Protected from light and in an airtight container |
Applications
Pimobendan is a first-line therapeutic drug for the treatment of congestive heart failure in dogs, specifically in:
▸ Dilated cardiomyopathy (DCM)
▸ Degenerative mitral valve disease (DMVD/CMVI)
How does Pimobendan work?
▸ Positive inotropic effect: Strengthens cardiac muscle contractions
▸ Vasodilation: Relaxes blood vessels, lowering resistance and improving circulation
▸ Improves oxygen delivery: Reduces symptoms like coughing, weariness, exercise intolerance, and rapid breathing
Clinical Benefits
▸ Increased exercise tolerance
▸ Reduced respiratory distress
▸ Improved quality of life
▸ Extended survival time in CHF patients
Administration
Pimobendan is given orally, and most dogs tolerate it well. Mild side effects, if any, may include:
Vomiting
▸ Diarrhea
▸ Loss of appetite
Because pimobendan affects cardiac function, veterinary supervision is required. Regular monitoring, such as echocardiography and blood testing, is necessary to ensure appropriate dose and safety.
Our Advantages
▸ GMP-certified manufacture
▸ DMF available
▸ High-grade raw materials
▸ Competitive price
▸ Reliable supply chain and expert technical support
Frequently Asked Questions
Q1: When was your company founded?
Our company was founded in 2019.
Q2: Do you accept small-quantity orders?
Yes, we accept modest orders. We see this as a fantastic opportunity to showcase our product quality and service.
Q3: Can you supply samples?
Absolutely. Samples are provided for quality evaluation.
Q4: Which payment options do you accept?
We accept T/T and L/C.
Conclusion
Pimobendan Pharmaceutical Grade (CAS 74150-27-9) is the leading first-line treatment for congestive heart failure in dogs. Its unique dual inodilator action - strengthening cardiac contractions while simultaneously reducing vascular resistance - delivers clinically proven improvements in survival time, exercise tolerance, and overall quality of life. With GMP-certified manufacturing, DMF availability, and reliable supply, it remains an essential API for veterinary cardiac formulations worldwide.
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