Dinoprost (CAS 551-11-1)
Properties, Uses, and Veterinary Applications
Dinoprost, also known as Prostaglandin F₂α (PGF₂α) , is a naturally occurring prostaglandin widely used in veterinary medicine for reproductive management. Known for its potent ability to induce uterine contractions and soften the cervix, Dinoprost plays a crucial role in inducing labor, terminating pregnancy, and treating reproductive disorders in livestock.
▸ CAS Number: 551-11-1
▸ Standards: JP, In-House Standard
What is Dinoprost?
Dinoprost (PGF₂α) is a hormone-like compound naturally produced in mammals and essential for reproductive regulating functions. As a pharmaceutical ingredient, it is used to replicate and enhance these physiological effects.
By acting directly on the myometrium (the muscular layer of the uterus), Dinoprost stimulates strong, coordinated uterine contractions and promotes cervical softening and dilation, making it effective for:
▸ Artificial abortion
▸ Late-term labor induction
▸ Treatment of reproductive disorders in animals
Product Details
| Property | Value |
|---|---|
| Molecular Formula | C₂₀H₃₄O₅ |
| Molar Mass | 354.49 g/mol |
| Density | ~1.0458 (estimate) |
| Melting Point | 25–35°C |
| Boiling Point | ~407.69°C (estimated) |
| Specific Rotation | D25 +23.5° (c = 1 in tetrahydrofuran) |
| Flash Point | 289°C |
| Vapor Pressure | 1.71E-13 mmHg at 25°C |
| pKa | ~4.90 (uncertain) |
| Refractive Index | 1.6120 (estimate) |
| Appearance | Powder |
| Color | White |
| Storage | Store airtight, protected from light, below 5°C (JP standard) |
These characteristics ensure stability and consistency for pharmaceutical and veterinary formulations.
Applications of Dinoprost (PGF₂α)
Dinoprost is widely used across veterinary medicine-especially in livestock breeding and reproductive management. It is also commercially known as Lutalyse .
Inducing Labor in Cows
▸ Inducing labor at term
▸ Managing delayed partitions
▸ Resolving reproductive disorders
Pregnancy Termination in Horses
Used in equine medicine to terminate early pregnancy or manage reproductive complications requiring controlled uterine contraction.
Treating Reproductive Conditions
▸ Luteal cysts
▸ Pyometra
▸ Anestrus
▸ Post-calving complications
How It Works
Dinoprost functions as a synthetic equivalent of endogenous PGF₂α. It induces luteolysis and stimulates uterine contraction , allowing precise reproductive cycle control and improved herd fertility management.
Packaging & Delivery Options
▸ Express delivery (FedEx, DHL)
▸ Air transportation for rapid international shipping
▸ Secure packaging to ensure product integrity
FAQs
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Conclusion
Dinoprost (CAS 551-11-1) is an essential prostaglandin extensively used in veterinary reproductive management. Its ability to stimulate uterine contractions, soften the cervix, and regulate reproductive cycles makes it invaluable in livestock operations and equine care. With strict quality standards, stable physicochemical properties, and flexible delivery options, Dinoprost remains a trusted and effective ingredient in reproductive health solutions.
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