API D-Cloprostenol Sodium Pharmaceutical Grade
High-Potency Synthetic Prostaglandin for Advanced Reproductive Control
Product Overview
D-Cloprostenol Sodium is a highly potent synthetic analogue of prostaglandin F₂α (PGF₂α) . As the dextrorotatory enantiomer of cloprostenol, it possesses significantly higher biological activity than the racemic mixture, making it a critical tool for precision reproductive management in cattle, swine, horses, and small ruminants .
Product Name: D-Cloprostenol Sodium API
CAS Number: 62561-03-9
Quality Standard: In-House / IP / EP / BP Standard
Category: Veterinary Active Pharmaceutical Ingredient (API)
By inducing rapid luteolysis, D-Cloprostenol Sodium allows producers and veterinarians to synchronize estrus and manage breeding schedules with exceptional accuracy.
Mechanism of Action
D-Cloprostenol Sodium acts specifically on the PGF₂α receptors in the corpus luteum to:
▸ Trigger luteolysis (regression of the corpus luteum)
▸ Induce a rapid drop in progesterone levels
▸ Initiate the return to estrus and follicular development
▸ Stimulate smooth muscle activity in the reproductive tract
Veterinary Applications
1. Estrus Synchronization & Breeding
Used extensively in cattle, sheep, and goats to facilitate timed artificial insemination (TAI) by:
▸ Synchronizing heat cycles across large herds
▸ Reducing the time required for estrus detection
▸ Optimizing labor efficiency during breeding windows
2. Treatment of Reproductive Disorders
D-Cloprostenol Sodium is an essential therapeutic agent for clinical conditions such as:
▸ Cystic ovarian disease and persistent corpus luteum
▸ Chronic endometritis and pyometra
▸ Retained fetal membranes in dairy cows
▸ Silent heat management
3. Swine, Equine & Ophthalmic Use
Broad clinical utility across specialized veterinary fields:
▸ Swine: Inducing farrowing for synchronized parturition
▸ Equine: Regulating estrous cycles and managing ovulation in mares
▸ Ophthalmology: Managing intraocular pressure and inducing miosis
Benefits for Livestock Operations
▸ Superior potency allows for smaller dose volumes
▸ Increases pregnancy rates and improves calving intervals
▸ Supports higher productivity in dairy and meat production
▸ Streamlines farm management through synchronized labor
Manufacturing & Company Profile
Henan Medscience Pharmaceuticals Co., Ltd.
Henan Medscience Pharmaceuticals is a State-recognized High-Tech Enterprise dedicated to the highest global standards of API production:
▸ Cutting-edge Prostaglandin R&D
▸ GMP-compliant sterile manufacturing facilities
▸ Stringent quality control for international markets
Conclusion
API D-Cloprostenol Sodium (CAS 62561-03-9) is an indispensable tool in modern veterinary medicine. Its unmatched luteolytic power makes it the preferred choice for estrus synchronization and the treatment of complex reproductive disorders. When high-performance livestock management is the goal, D-Cloprostenol Sodium provides the precision and reliability required for success.
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