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API Dexmedetomidine Hydrochloride CAS 145108-58-3

API Dexmedetomidine Hydrochloride CAS 145108-58-3

CAS Number: 145108-58-3
Standard: In-house standard
Dexmedetomidine hydrochloride is a medication that is commonly used in veterinary medicine as a sedative and analgesic agent. It is a powerful alpha-2 agonist, which means it binds to and stimulates alpha-2 receptors in the brain, causing sedation, analgesia, and muscle relaxation. Dexmedetomidine hydrochloride is primarily used in veterinary medicine for small animal and large animal procedures.
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Product Introduction

API Dexmedetomidine Hydrochloride

CAS 145108-58-3 | Advanced Veterinary Sedation & Analgesia API

Dexmedetomidine Hydrochloride is a highly effective veterinary active pharmaceutical ingredient (API) widely used for sedation, analgesia, and muscle relaxation in animals. Known for its reliability and favorable safety profile, this compound plays a critical role in modern veterinary anesthesia and procedural care.

Basic Information

Product Name: Dexmedetomidine Hydrochloride

CAS Number: 145108-58-3

Standard: In-house standard

Category: Alpha-2 adrenergic receptor agonist

Intended Use: Veterinary pharmaceutical formulations

Pharmacological Overview

Dexmedetomidine Hydrochloride is a potent and selective alpha-2 adrenergic agonist. By stimulating alpha-2 receptors in the central nervous system, it produces dose-dependent sedation, analgesia, and muscle relaxation.

Unlike many sedatives, it provides these effects with minimal respiratory depression, making it particularly suitable for veterinary use across a wide range of species. The API is valued for its rapid onset of action, predictable effects, and relatively short duration, allowing veterinarians to perform procedures efficiently while maintaining a high margin of safety.

Applications in Veterinary Medicine

Dexmedetomidine Hydrochloride is extensively used in both small and large animal practice, either alone or in combination with other anesthetic or analgesic agents.

Use in Small Animals

In small animals such as dogs, cats, and selected exotic species (including ferrets and hedgehogs), it is commonly employed for:

▸ Diagnostic imaging and examinations

▸ Minor surgical procedures

▸ Dental treatments

▸ Pre-anesthetic sedation and calming

It may be administered intramuscularly or orally, depending on the clinical situation. In dental and minor surgical procedures, it is often combined with ketamine and appropriate analgesics to enhance anesthesia quality and patient comfort.

Use in Large Animals

In large animal veterinary practice, including horses and cattle, it is widely used for:

▸ Standing surgeries

▸ Diagnostic procedures

▸ Joint, tendon, or soft tissue treatments

Its ability to provide effective sedation and analgesia without significant cardiovascular or respiratory suppression makes it especially suitable for procedures where the animal must remain standing and stable.

Key Advantages

▸ Provides reliable sedation, analgesia, and muscle relaxation

▸ Rapid onset with controlled duration of action

▸ Minimal respiratory and cardiovascular depression

▸ Suitable for both small and large animals

▸ Enhances animal safety and procedural efficiency

When used according to recommended veterinary guidelines, Dexmedetomidine Hydrochloride significantly improves animal welfare and procedural outcomes.

Quality and Safety Considerations

As a potent sedative agent, Dexmedetomidine Hydrochloride should always be administered under professional veterinary supervision. Accurate dosing and proper monitoring are essential to ensure optimal therapeutic results and animal safety, particularly during repeated or combined drug use.

About the Manufacturer

Xiamen Origin Biotech Co., Ltd. is located in the Xiamen Torch Hi-tech Industrial Development Zone and is recognized as a State Hi-tech Enterprise. The company integrates research and development, manufacturing, and global sales of human and veterinary pharmaceutical products. Its portfolio includes hormones, proteins and peptides, prostaglandins, and small molecular compounds, serving pharmaceutical manufacturers worldwide.

Supply & Service Information

Product Availability: Most products are readily available in stock

Minimum Order Quantity (MOQ): Determined based on product requirements

Transportation: Express delivery (such as FedEx) or air transportation available

Pricing: Direct factory supply ensures competitive and cost-effective pricing

For detailed specifications, technical support, or quotations, customers are encouraged to contact the supplier directly.

 

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