Dexmedetomidine Hydrochloride
Sedative & Anesthetic for Modern Human Medicine
Product Overview
Dexmedetomidine Hydrochloride is a highly selective α2-adrenergic receptor agonist widely used in modern clinical practice. It provides effective sedation, anxiolysis, and analgesia while minimizing respiratory depression. It is especially valuable in intensive care units (ICUs), operating rooms, and perioperative settings.
CAS Number: 145108-58-3
Standard: In-House / GMP Compliant
Technical Specifications
Molar Mass: 236.74
Density: 1.17 g/cm³
Melting Point: 156.5–157.5°C
Boiling Point: 381.9°C at 760 mmHg
Flash Point: 191.3°C
Solubility: Soluble in water (100 mM), DMSO (48 mg/ml), ethanol (48 mg/ml)
Vapor Pressure: 1.08E-05 mmHg at 25°C
Appearance: Crystalline powder
Color: White to Off-White
Storage Condition: 2–8°C
What is Dexmedetomidine?
Dexmedetomidine induces sedation while allowing patients to remain arousable and cooperative. Unlike traditional sedatives, it preserves respiratory function, making it ideal for conscious sedation procedures.
Common administration routes include:
- Intravenous (IV) injection
- Intramuscular (IM) injection
- Oral administration
Key Applications
1. Intensive Care Sedation
Used for long-term sedation of mechanically ventilated patients in ICUs. It reduces anxiety and agitation while supporting hemodynamic stability.
2. Perioperative & Preoperative Care
- Reduces preoperative anxiety
- Enhances analgesia
- Lowers anesthetic requirements
- Improves postoperative recovery
3. Procedural Sedation
Provides safe, controllable sedation during diagnostic or minor surgical procedures. Often combined with opioids or benzodiazepines for enhanced effectiveness.
4. Postoperative Management
Helps manage postoperative pain, minimize delirium and agitation, and reduce opioid requirements for faster recovery.
Advantages
- Effective sedation with minimal respiratory depression
- Flexible administration routes
- Enhances analgesia
- Reduces additional anesthetic requirements
- Clinically validated for ICU and surgical use
Our Strengths
Strict Quality Control: Full control from raw materials to environmental monitoring.
Best Customer Service: Full technical documentation and tailored pharmaceutical solutions.
Conclusion
Dexmedetomidine Hydrochloride is a versatile and reliable sedative essential for ICU care, perioperative management, and procedural sedation. Its balance of safety, effectiveness, and flexibility makes it indispensable in modern clinical medicine.
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