Product Details

CAS Number: 790299-79-5
Standard: In-House Standard
Molecular Formula: C₂₈H₃₀N₆OS
Molar Mass: 498.64 g/mol
Density: 1.280 ± 0.06 g/cm³ (Predicted)
Melting Point: 90–95°C
Appearance: Solid
Color: Off-White to Pale Beige
pKa: 13.24 ± 0.70 (Predicted)
Storage Condition: Refrigerated

What is Masitinib?

Masitinib, also known as Masitinib Mesylate, is a next-generation tyrosine kinase inhibitor (TKI) targeting enzymes involved in cancer progression, inflammation, and immune system activation. It inhibits mast cells and microglia, reducing inflammation and neurodegeneration. Originally developed for oncology, it also shows benefits in chronic inflammatory and CNS disorders due to its immunomodulatory effects.

Applications of Masitinib

1. Treatment of Cancer (Mastocytosis & GIST)

Masitinib is formulated as an oral medication for cancers such as:

• Mastocytosis
• Gastrointestinal stromal tumors (GIST)

By blocking enzymes driving tumor growth, it helps slow tumor progression, reduce spread, and improve patient survival. Often used alone or with chemotherapy, surgery, or radiation.

2. Support in Inflammatory & Immune-Related Disorders

Masitinib treats diseases linked to chronic inflammation and immune dysregulation, including:

• Inflammatory diseases
• Central nervous system disorders
• Conditions with progressive neurodegeneration

Inhibiting mast cell and microglial activation helps reduce inflammation, protect nerves, and manage degenerative disease symptoms.

3. Reduction of Disease Recurrence

Masitinib may lower the risk of cancer recurrence, serving as valuable long-term maintenance therapy.

Why Choose Us

1. Extensive Production Experience

Over a decade of professional pharmaceutical manufacturing since 2013 guarantees expertise and reliability in every batch.

2. Strict Quality Control

We follow rigorous quality assurance including:

• Raw material qualification
• Environmental monitoring
• Full GMP compliance

Ensures consistent purity, safety, and reliability.

3. Completed Manufacturing System

Our 2,523 m² GMP-compliant workshop supports stable, large-scale production.

Frequently Asked Questions (FAQs)

Q1: Is your company a manufacturer?

Yes. We operate our own production facility and manage all manufacturing processes internally.

Q2: Can we visit your factory for a quality audit?

Absolutely. Customers are welcome to visit for audits. Contact us to schedule.

Conclusion

Masitinib (CAS 790299-79-5) is a powerful targeted therapy. Its dual ability to treat cancer and manage inflammatory or neurodegenerative diseases makes it essential in modern pharmaceutical research and clinical practice. With proven therapeutic benefits and strong immunomodulatory activity, Masitinib offers hope for improved outcomes in challenging conditions.