Avibactam Sodium
Advanced β-Lactamase Inhibitor for Resistant Gram-Negative Infections
Introduction
CAS Number: 1192491-61-4
Standard: In-House / IP / EP / BP Standard
Avibactam Sodium is a non-β-lactam β-lactamase inhibitor used to combat resistant Gram-negative bacterial infections. It effectively inhibits key β-lactamase enzymes including KPC, ESBL, and AmpC, helping restore the activity of carbapenems, cephalosporins, and penicillins.
As a dedicated manufacturer, we provide high-quality, compliant, and reliable supply of Avibactam Sodium for global pharmaceutical partners.
Applications
The rapid rise of antibiotic resistance has created urgent demand for innovative therapeutic solutions. Avibactam Sodium represents a significant advancement, offering strong activity against MDR and XDR Gram-negative pathogens.
FDA-Approved Combination Therapy
In combination with Ceftazidime, it is indicated for complicated intra-abdominal infections (cIAI), complicated urinary tract infections (cUTI), hospital-acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP).
Aztreonam Combination Option
Provides an essential treatment alternative for patients with limited therapeutic options due to highly resistant pathogens.
Broad Enzyme Inhibition
Effectively inhibits KPC, ESBL, AmpC, and other β-lactamases, restoring antibiotic efficacy against resistant strains.
Key Advantages
Broad-Spectrum Activity: Effective against a wide range of resistant Gram-negative bacteria.
Synergistic Performance: Works synergistically with partner antibiotics to improve therapeutic outcomes.
Manufacturing Excellence
As a professional manufacturer, we ensure consistent quality, regulatory-compliant production, and stable global supply. Our advanced manufacturing capabilities support pharmaceutical partners in developing and producing high-quality anti-infective formulations.
Conclusion
Avibactam Sodium is a vital tool in combating antibiotic resistance. With proven efficacy, safety, and combination flexibility, it continues to play a crucial role in improving clinical outcomes and addressing global antimicrobial challenges.
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