Cloprostenol Sodium (CAS 55028-72-3)
A Reliable Prostaglandin API for Veterinary Reproductive Management
Cloprostenol Sodium is a synthetic prostaglandin F₂α analogue widely authorized for veterinary use, especially in beef and dairy cattle . It is primarily used to induce luteolysis , making it an essential product for managing reproductive cycles and treating hormone-related reproductive disorders.
▸ CAS Number: 55028-72-3
▸ Quality Standards: IP / BP / In-house
▸ Category: Veterinary Reproductive Hormone API
Thanks to its predictable biological activity and strong luteolytic effect, Cloprostenol Sodium is commonly applied in controlled breeding programs and fertility management protocols.
Product Overview & Physical Properties
Molecular Formula: C₂₂H₃₀ClNaO₆
Molar Mass: 448.92
Appearance: Amorphous powder
Color: White or almost white
Thermal & Chemical Properties
Melting Point: 68–70 °C
Boiling Point: 628 °C (760 mmHg)
Flash Point: 333.6 °C
Solubility: >10 mg/mL in water
Vapor Pressure: 1.23E-16 mmHg at 25 °C
Storage Conditions
Store at 2–8 °C , protected from light and moisture, to maintain product stability and potency.
Mechanism of Action
▸ Regression of the corpus luteum
▸ Rapid decline in progesterone levels
▸ Induction of estrus and ovulation
▸ Stimulation of uterine contractions
These actions make it highly effective for reproductive control and therapeutic interventions in livestock and equine practice.
Veterinary Applications
Use in Cattle
▸Induction and synchronization of estrus
▸ Support for timed breeding and artificial insemination
▸ Treatment of persistent corpus luteum
▸ Management of cystic ovaries
▸ Treatment of pyometra and chronic endometritis
▸ Expulsion of mummified fetuses
▸ Induced abortion following mismating
▸ Addressing unobserved estrus in normally cycling cows
These applications help improve conception rates and overall herd reproductive efficiency.
Use in Horses
▸ Induction and synchronization of estrus in mares
▸ Facilitating scheduled breeding programs
▸ Treatment of persistent corpus luteum
▸ Management of uterine infections and cysts
Its reliable action makes it an important tool for stud farms and equine veterinarians.
Key Advantages
▸Strong and selective luteolytic activity
▸ Predictable estrus induction
▸ Broad use in cattle and horses
▸ Supports efficient breeding management
▸ Manufactured according to recognized pharmacopeial standards
Sales, Supply & Global Services
Henan Medscience actively develops both domestic and international markets and welcomes long-term partnerships worldwide.
▸ Europe
▸ North America
▸ South America
▸ Middle East
▸ Asia
Products are well recognized for reliability, regulatory compliance, and professional after-sales support.
Documentation Support
▸ GMP Certificate
▸ Drug Master File (DMF)
▸ Certificate of Analysis (COA)
▸ Material Safety Data Sheet (MSDS)
Frequently Asked Questions (FAQs)
Q1: Can the packaging be customized?
Yes. Various glass bottle and foil bag sizes are available, including small packs and bulk packaging options.
Q2: Can different batches be mixed in a start order?
Yes, mixing different batches is acceptable.
Q3: Can you provide COA and MSDS?
Yes, both documents can be provided upon request.
Conclusion
Cloprostenol Sodium (CAS 55028-72-3) is a highly effective and trusted veterinary prostaglandin API used for estrus synchronization, fertility management, and treatment of reproductive disorders in cattle and horses. With reliable quality, pharmacopeial compliance, and broad clinical applications, it remains a cornerstone ingredient in modern veterinary reproductive formulations.
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